Questions of control of hormone content in fish and other aquatic organisms (metaanalysis)

Between 1995 and 2018, the production of fish fishery products using feed increased from 12 to 54.3 million tons. In cultivation such in many countries, hormones are widely used as growth stimulants increase efficiency conversion for purpose sex reversal, well artificial reproduction. Hormones, especially their synthetic forms, poorly metabolized marine organisms, which leads accumulation food matrix. When they enter human body, capable tissues, affect endocrine system can cause development a number metabolic disorders. The possibility carcinogenic effect has been proven. data presented substantiate need control content products, develop highly sensitive methods detection, establish list controlled hormone-like drugs safety regulations produced with use. most accurate method this case is HPLC-MS/MS method. We believe that natural (non-synthetic hormones) hormones, criterion absence sample should be sensitivity threshold research (at least 20 ng/kg).